All-In Podcast
All-In Podcast
Industry veterans, degenerate gamblers & besties Chamath Palihapitiya, Jason Calacanis, David Sacks & David Friedberg cover all things economic, tech, political, social & poker.
Jason CalacanisChamath PalihapitiyaDavid SacksDavid Friedberg
PodcastAI
PodcastAI

Trump Takes On the Fed, US-Intel Deal, Why Bankruptcies Are Up, OpenAI's Longevity Breakthrough

E241 • Aug 30, 2025 • 92 mins

The episode kicks off with a lively introduction from the J-Cal Ranch, followed by updates on the All-In Summit and Jason's new program. The discussion then turns to Trump's contentious relationship with the Federal Reserve, questioning its partisanship and envisioning a modernized Fed. The US-Intel deal is analyzed for its sustainability and potential to bolster Social Security, drawing comparisons with China's strategies. The idea of a US Sovereign Wealth Fund is explored, along with the rising trend of corporate bankruptcies projected for 2025. The episode concludes with a look at OpenAI's innovative use of large language models in longevity research.

Key Points

  • Chamath believes the Federal Reserve is inherently political and suggests that many of its functions, particularly monetary policy and price stability, could be better handled by the free market and Treasury.
  • The U.S. government's decision to take a 10% equity stake in Intel in exchange for grants is seen as a positive move, aligning taxpayer interests with corporate success, though concerns were raised about the aggressive negotiation tactics used.
  • The use of Yamanaka factors combined with advancements in AI-driven protein sequencing is showing promising results in reversing cellular aging, potentially paving the way for significant breakthroughs in human longevity.
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