OpenAI Misses Targets, Codex vs Claude, Elon vs Sam Trial, Big Hyperscaler Beats, Peptide Craze
May 1, 2026 • 81 minsThe episode begins with a light discussion on favorite podcasts and games, then delves into OpenAI's advancements and challenges in product development and energy use. It covers Google's Gemini in the AI market and cybersecurity in AI models. The Musk vs. Altman trial and the impact of therapy on leadership are analyzed. Big tech earnings, capital market shifts, and AI's economic implications are explored. The episode examines AI's risks and benefits in software development, highlights Retatrutide clinical trial results, Friedberg's Supreme Court experience, and discusses decision-making and public trust in the Supreme Court before concluding with closing remarks.
Can a British-Born Republican Actually Win the California Governor's Race?
Apr 29, 2026 • 69 minsThe episode introduces Steve Hilton, exploring his political evolution and comparing California's current state to the UK in the 1970s. It covers Hilton's tax policy proposals, addressing California's fiscal inefficiencies, and the challenges of tax cuts in a Democrat-led legislature. The discussion shifts to California's high cost of living, housing crisis, and regulatory hurdles, including the impact of climate regulations on energy costs. The state's education system, crime, law enforcement, and homelessness are scrutinized. Finally, Hilton's campaign strategy and policy vision are outlined.
SpaceX-Cursor Deal, SaaS Debt Bomb, New Apple CEO, SPLC Indictment, Colon Cancer Spike
E270 • Apr 24, 2026 • 91 minsThe episode begins with the strategic implications of the SpaceX-Cursor deal and its potential to leverage compute power. The discussion shifts to the SaaS industry's challenges, including a looming debt crisis and investment strategies. The focus then turns to Apple's leadership transition as John Ternus takes over as CEO and the possible future directions for the company. The conversation addresses the indictment of the SPLC and the broader implications for NGOs. The Science Corner segment explores recent findings on the rise in colorectal cancer among young adults, wrapping up with insights and reflections.
OpenAI's Identity Crisis, Datacenter Wars, Market Up on Iran News, Mamdani's First Tax, Swalwell Out
E268 • Apr 17, 2026 • 91 minsThe episode opens with a discussion on pied-à-terre taxes in major cities before diving into OpenAI's identity crisis and its competition with Anthropic. The conversation shifts to the dynamics of legacy tech companies, acquisitions, and the challenges faced by Anthropic. They explore the dependency on compute resources and recent market shifts. The discussion then moves to Allbirds' AI pivot, valuation trends, and regulatory impacts. Energy solutions and public perceptions of data centers are examined. The episode explores AI leadership, political scandals, and media coverage, wrapping up with market insights from Warren Buffett, AI's role in efficiency, and a game show segment. It concludes with closing remarks and lighthearted banter.
Anthropic’s $30B Ramp, Mythos Doomsday, OpenClaw Ankled, Iran War Ceasefire, Israel's Influence
E267 • Apr 10, 2026 • 89 minsThe episode kicks off with friends catching up on Anthropic's Mythos model controversy and the rise of AGI models. They discuss AI safety, industry-government coordination, and challenges in security and open-source software. They explore OpenClaw's strategy, Anthropic's growth, compute costs, and AI investments. The conversation moves to Polymarket IPOs, venture capital trends, and the future of enterprise software. It also touches on geopolitical tensions in Iran, X's auto-translate feature, and community engagement, wrapping up with updates on the All-In Summit and personal anecdotes.
Josh Shapiro on Trump, Iran War Chaos, Israel's Failure, the Economy, and 2028 Race
Apr 8, 2026 • 62 minsJosh Shapiro shares his journey as Governor of Pennsylvania, discussing sports fandom, government efficiency, and public trust. He outlines strategies to combat fraud, waste, and abuse, alongside pro-business initiatives and tax cuts. The conversation covers wealth disparity, federal tax policies, and Democratic Party strategies, including VP selection. Economic issues, Trump's policies, housing, college affordability, and socialist movements are examined. The discussion also touches on Congress' role, collaboration challenges, corruption allegations, and the Israel-Palestine conflict, concluding with Shapiro's closing thoughts and future guest plans.
The State of Modern War: Palantir & Anduril Execs on Drones, AI, and the End of Traditional Warfare
Apr 6, 2026 • 69 minsShyam Sankar and Trae Stephens discuss the evolution of defense technology in Silicon Valley. They explore Palantir's origins, the region's shifting attitudes toward defense tech, and the role of Silicon Valley in national defense. The conversation covers defense readiness challenges, Anduril's innovative Arsenal One factory, and the shift from software to hardware. They emphasize the need for government investment and bipartisan support for innovation. Topics also include ethics in warfare, tech companies' responsibilities, and the cultural disconnect between elite institutions and the military. Finally, they discuss the future of American leadership and education in a multipolar world.
SpaceX IPO, Iran War Fallout, Quantum Bitcoin Hack, The Space Opportunity
E266 • Apr 3, 2026 • 81 minsThis episode explores the potential SpaceX IPO and its impact on Tesla, highlighting Elon Musk's leadership and the future of space exploration. Topics include SpaceX's role in internet access, data centers, and reducing space costs. Economic opportunities in space, like mining, robotics, and tourism, are discussed. The hosts also analyze the IPO surge, market risks, and AGI's effect on valuations. They touch on investor competition, early public offering performance, Middle Eastern capital flows, the Iran conflict, energy independence, and quantum computing's cybersecurity risks. The episode concludes with Friedberg's potato seed update, poker stories, and reflections on DAOs and Chamath's Tau.
Anthropic's Generational Run, OpenAI Panics, AI Moats, Meta Loses Major Lawsuits
E265 • Mar 27, 2026 • 80 minsThe episode kicks off with updates and banter before exploring Anthropic's strategy against OpenAI and its market implications. The hosts discuss OpenAI's market share, enterprise focus, and private equity's role in AI. They cover consumer AI apps, subscription trends, and monetization models, followed by Google's AI initiatives and Workspace Studio automation. They evaluate company valuations and superintelligence's market influence, emphasizing business durability. The episode also addresses AI's impact on productivity, Meta's legal challenges regarding child safety, and broader tech implications. It concludes with thoughts on President Trump's science council and industrial tech leadership.
Four CEOs on the Future of AI: CoreWeave, Perplexity, Mistral, and IREN
Mar 24, 2026 • 98 minsLive from NVIDIA's GTC conference, Jason Calacanis hosts Michael Intrator, Aravind Srinivas, and Arthur Mensch to discuss the future of GPU technology and AI. They explore CoreWeave's journey from GPU adoption to crypto mining, and strategies for risk management and scaling. Topics include large-scale computing, GPU demand, and financing. Aravind Srinivas talks about Perplexity AI's evolution and future operating systems, while Arthur Mensch covers Mistral AI's NVIDIA partnership and synthetic data. Daniel Roberts wraps up with insights on Iris Energy's renewable data centers and trends in custom silicon and nuclear energy computing.
Is THIS California's Next Governor? Matt Mahan's Bold Plan for the Golden State
Mar 23, 2026 • 77 minsIn this episode, David Friedberg chats with Matt Mahan about his political journey and civic tech efforts in California. Mahan discusses government inefficiencies, his achievements in San Jose, and legislative motivations. They explore labor unions, political incentives in Sacramento, and issues like homelessness, mental health, and housing affordability. Mahan also tackles the drug crisis, public safety, green energy policies, and challenges with homeowners insurance and public employee retirement liabilities. They examine California's state budget, healthcare, economic inequality, and the political landscape, including Governor Newsom's performance and immigration policy.
Jensen Huang: Nvidia's Future, Physical AI, Rise of the Agent, Inference Explosion, AI PR Crisis
Mar 19, 2026 • 67 minsIn this episode featuring Jensen Huang, we explore the global tech and AI landscape, focusing on NVIDIA's role in AI computing and future strategies. Discover Grok's impact, embedded AI applications, data centers, and NVIDIA's decision-making. We discuss AI's influence on industries, open-source development, and regulatory issues. Topics include AI model diversity, efficiency, global tech diffusion, national security, and supply chain impacts. NVIDIA's strategies in autonomous vehicles and AI hardware competition are highlighted, along with revenue predictions, data centers in space, and AI's healthcare role. Concluding with robotics and AI's economic effects across sectors.
The Democrat Republicans Actually Like: John Fetterman Unfiltered
Mar 18, 2026 • 45 minsJoin David Friedberg as he hosts Senator John Fetterman to explore the Save America Act and the Democratic Party's current trajectory. Fetterman shares insights on bipartisanship, his Republican appeal, and international issues like Iran and NATO. He discusses his views on Israel, AIPAC, and anti-Israel sentiment, as well as domestic topics such as voter ID laws, election fraud, immigration, and Biden's border policies. The episode also covers the national debt, government fraud, wealth tax proposals, anti-AI sentiment, and the state of agriculture, providing a comprehensive look at Fetterman's political stance and continued Democratic allegiance.
Two Legendary Founders: Travis Kalanick & Michael Dell Live from Austin, Texas
Mar 17, 2026 • 76 minsThe episode kicks off with Travis Kalanick discussing his new venture, Adams, which operates in stealth mode. The conversation explores mining, automation, and self-driving technology, as well as the future of cities like Austin and San Francisco amid tech's political hurdles. AI and robotics are examined as strategic business tools. Michael Dell shares insights into Texas's growth and AI infrastructure, focusing on ROI, economic incentives, and the rapid adoption of AI. The dialogue extends to the future of AI, AGI, and superintelligence, alongside the social impact and the Invest America Act. Dell's philanthropic efforts and initiatives like child investment accounts are highlighted before closing thoughts and acknowledgments.
Iran War, Oil Shock, Off Ramps, AI's Revenue Explosion and PR Nightmare
E264 • Mar 13, 2026 • 80 minsThe episode opens with a discussion on the economic consequences of the Iran War, exploring potential escalation scenarios and their impact on the midterm elections. The conversation covers possible off-ramp strategies, the involvement of Gulf states, and China's influence on the situation. Attention shifts to Anthropic and OpenAI, examining their unprecedented revenue growth. The speakers then address AI's public relations challenges and the future of open-source development. The episode concludes with an analysis of Washington's newly passed "Millionaire Tax" and Howard Schultz's decision to relocate to Miami.
Inside the Iran War and the Pentagon's Feud with Anthropic with Under Secretary of War Emil Michael
E263 • Mar 6, 2026 • 83 minsEmil Michael joins to discuss the broader implications of the US military actions against Iran and the timing behind them. The conversation delves into Trump's evolving warfare strategies, focusing on AI, drone technology, and new rules of engagement. Israel's involvement in the conflict and its strategic partnership with the US, including the Iron Beam defense system, are analyzed. The economic ramifications of the conflict, particularly oil prices and Trump's maritime insurance strategy, are explored. The episode also examines the Pentagon's decision to label Anthropic a supply-chain risk, its impact on valuation, and the state of the US defense supply chain. Finally, insights into DARPA's role and China's military posture are offered.
Software Stocks Implode, Claude's Hit List, State of the Union Reactions, Trump's Tariff Pivot
E262 • Feb 27, 2026 • 81 minsThe episode begins with Claude's controversial list and the ongoing SaaS market downturn. The discussion then shifts to Citrini's AI letter and the rising popularity of doomer narratives, while highlighting emerging AI job opportunities. The Rate Payer Protection Pledge and the growing opposition to data centers are examined in detail. Reactions to the State of the Union address are shared, followed by a Science Corner segment exploring the potential of Yamanaka Factors in curing blindness. The episode concludes with insights into the recent SCOTUS decision on tariffs and Trump's subsequent strategic pivot.
Prince Andrew Arrested, Epstein Mythology, Reid Hoffman Files with Saagar Enjeti & Michael Tracey
Bonus • Feb 20, 2026 • 107 minsIn this episode, we explore Jeffrey Epstein's network and the media's portrayal of his crimes. Guests discuss Prince Andrew's arrest and Epstein's influence, critiquing the media's role in shaping public perception and questioning Epstein's wealth origins. We examine Les Wexner's deposition, Virginia Roberts Guiffre's claims, and the "Filthy Rich" documentary. The episode also covers financial settlements, the Epstein Victims Compensation Fund, and class action lawsuits. Kevin Bass talks about using AI to analyze Epstein files and the implications of guilt by association, concluding with the role of citizen journalism in the Epstein saga.
Debt Spiral or NEW Golden Age? Super Bowl Insider Trading, Booming Token Budgets, Ferrari's New EV
E261 • Feb 14, 2026 • 73 minsThe episode kicks off with a warm welcome and dives into the rapid acceleration of AI, examining its transformative impact on the workforce. The conversation shifts to AI's role in venture capital, addressing enterprise concerns about integration and disruption. The hosts explore prediction markets and their societal implications, followed by an announcement for the upcoming All-In event, "Liquidity." They analyze the new Congressional Budget Office report, discussing the implications of the US debt spiral. The economic outlook is further dissected through the lens of employment and minimum wage debates. Finally, the episode touches on Ferrari's new electric vehicle, sparking a broader discussion on the luxury car market before wrapping up.
Epstein Files, Is SaaS Dead?, Moltbook Panic, SpaceX xAI Merger, Trump's Fed Pick
E260 • Feb 6, 2026 • 79 minsIn this episode, Brad Gerstner joins the hosts to discuss Ohalo's potato seed technology and the Epstein files release. They critique media narratives and the declining value of SaaS companies. The role of AI in shaping future uncertainties and its impact on SaaS is explored, with Brad highlighting potential AI beneficiaries. They also discuss MoltBook's AI issues, Kevin Warsh's Federal Reserve nomination, and the SpaceX and X.AI merger. The episode concludes with insights on AI tools, Brad's America accounts initiative, and the need for Social Security reform amid government spending concerns.





